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Heterologous prion-forming proteins interact to cross-seed aggregation in Saccharomyces cerevisiae
The early stages of protein misfolding remain incompletely understood, as most mammalian proteinopathies are only detected after irreversible protein aggregates have formed. Cross-seeding, where one aggregated protein templates the misfolding of a heterologous protein, is one mechanism proposed to s...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5517628/ https://ncbi.nlm.nih.gov/pubmed/28724957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05829-5 |
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