Control of cytokine mRNA degradation by the histone deacetylase inhibitor ITF2357 in rheumatoid arthritis fibroblast-like synoviocytes: beyond transcriptional regulation

BACKGROUND: Histone deacetylase inhibitors (HDACi) suppress cytokine production in immune and stromal cells of patients with rheumatoid arthritis (RA). Here, we investigated the effects of the HDACi givinostat (ITF2357) on the transcriptional and post-transcriptional regulation of inflammatory marke...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Arthritis Res Ther
Huvudupphovsmän: Angiolilli, Chiara, Kabala, Pawel A., Grabiec, Aleksander M., Rossato, Marzia, Lai, Wi S., Fossati, Gianluca, Mascagni, Paolo, Steinkühler, Christian, Blackshear, Perry J., Reedquist, Kris A., Baeten, Dominique L., Radstake, Timothy R. D. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053802/
https://ncbi.nlm.nih.gov/pubmed/30029685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1638-4
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk