Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes

BACKGROUND: Endoplasmic reticulum (ER) stress has proinflammatory properties, and transgenic animal studies of rheumatoid arthritis (RA) indicate its relevance in the process of joint destruction. Because currently available studies are focused primarily on myeloid cells, we assessed how ER stress m...

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Publicat a:Arthritis Res Ther
Autors principals: Kabala, Pawel A., Angiolilli, Chiara, Yeremenko, Nataliya, Grabiec, Aleksander M., Giovannone, Barbara, Pots, Desiree, Radstake, Timothy R., Baeten, Dominique, Reedquist, Kris A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604427/
https://ncbi.nlm.nih.gov/pubmed/28923079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1386-x
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