Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes

BACKGROUND: Endoplasmic reticulum (ER) stress has proinflammatory properties, and transgenic animal studies of rheumatoid arthritis (RA) indicate its relevance in the process of joint destruction. Because currently available studies are focused primarily on myeloid cells, we assessed how ER stress m...

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Pubblicato in:Arthritis Res Ther
Autori principali: Kabala, Pawel A., Angiolilli, Chiara, Yeremenko, Nataliya, Grabiec, Aleksander M., Giovannone, Barbara, Pots, Desiree, Radstake, Timothy R., Baeten, Dominique, Reedquist, Kris A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604427/
https://ncbi.nlm.nih.gov/pubmed/28923079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1386-x
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