Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes

BACKGROUND: Endoplasmic reticulum (ER) stress has proinflammatory properties, and transgenic animal studies of rheumatoid arthritis (RA) indicate its relevance in the process of joint destruction. Because currently available studies are focused primarily on myeloid cells, we assessed how ER stress m...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Kabala, Pawel A., Angiolilli, Chiara, Yeremenko, Nataliya, Grabiec, Aleksander M., Giovannone, Barbara, Pots, Desiree, Radstake, Timothy R., Baeten, Dominique, Reedquist, Kris A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604427/
https://ncbi.nlm.nih.gov/pubmed/28923079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1386-x
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