Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression

OBJECTIVES: Epigenetic modifications play an important role in the regulation of gene transcription and cellular function. Here, we examined if pro-inflammatory factors present in the inflamed joint of patients with rheumatoid arthritis (RA) could regulate histone deacetylase (HDAC) expression and f...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Ann Rheum Dis
Autores principales: Angiolilli, Chiara, Grabiec, Aleksander M, Ferguson, Bradley S, Ospelt, Caroline, Fernandez, Beatriz Malvar, van Es, Inge E, van Baarsen, Lisa G M, Gay, Steffen, McKinsey, Timothy A, Tak, Paul P, Baeten, Dominique L, Reedquist, Kris A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336378/
https://ncbi.nlm.nih.gov/pubmed/25452308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-205635
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares