Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells

While bone is a frequent target of breast cancer-associated metastasis, little is known about the effects of tumor-bone interactions on the efficacy of tumor-suppressing agents. Here we examined the effect of two FDA-approved dopamine modulators, Fluphenazine (FP) and Trifluoperazine (TFP), on mamma...

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Pubblicato in:Cancer Res
Autori principali: Liu, Shengzhi, Fan, Yao, Chen, Andy, Jalali, Aydin, Minami, Kazumasa, Ogawa, Kazuhiko, Nakshatri, Harikrishna, Li, Bai-Yan, Yokota, Hiroki
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050076/
https://ncbi.nlm.nih.gov/pubmed/29769195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0056
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