Inhibitory Effects of Dopamine Receptor D(1) Agonist on Mammary Tumor and Bone Metastasis

Dopaminergic signaling plays a critical role in the nervous system, but little is known about its potential role in breast cancer and bone metabolism. A screening of ~1,000 biologically active compounds revealed that a selective agonist of dopamine receptor D1 (DRD1), A77636, inhibited proliferation...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Minami, Kazumasa, Liu, Shengzhi, Liu, Yang, Chen, Andy, Wan, Qiaoqiao, Na, Sungsoo, Li, Bai-Yan, Matsuura, Nariaki, Koizumi, Masahiko, Yin, Yukun, Gan, Liangying, Xu, Aihua, Li, Jiliang, Nakshatri, Harikrishna, Yokota, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379485/
https://ncbi.nlm.nih.gov/pubmed/28374823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45686
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