Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling

Chemotherapy for suppressing tumor growth and metastasis tends to induce various effects on other organs. Using AZD7762, an inhibitor of checkpoint kinase (Chk) 1 and 2, the present study examined its effect on mammary tumor cells in addition to bone cells (osteoclasts, osteoblasts and osteocytes),...

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Udgivet i:Int J Oncol
Main Authors: Wang, Luqi, Wang, Yue, Chen, Andy, Jalali, Aydin, Liu, Shengzhi, Guo, Yunxia, Na, Sungsoo, Nakshatri, Harikrishna, Li, Bai-Yan, Yokota, Hiroki
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065446/
https://ncbi.nlm.nih.gov/pubmed/30015873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4481
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