Overexpression of Lrp5 enhanced the anti-breast cancer effects of osteocytes in bone

Osteocytes are the most abundant cells in bone, which is a frequent site of breast cancer metastasis. Here, we focused on Wnt signaling and evaluated tumor-osteocyte interactions. In animal experiments, mammary tumor cells were inoculated into the mammary fat pad and tibia. The role of Lrp5-mediated...

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Enregistré dans:
Détails bibliographiques
Publié dans:Bone Res
Auteurs principaux: Liu, Shengzhi, Wu, Di, Sun, Xun, Fan, Yao, Zha, Rongrong, Jalali, Aydin, Feng, Yan, Li, Kexin, Sano, Tomohiko, Vike, Nicole, Li, Fangjia, Rispoli, Joseph, Sudo, Akihiro, Liu, Jing, Robling, Alexander, Nakshatri, Harikrishna, Li, Bai-Yan, Yokota, Hiroki
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260600/
https://ncbi.nlm.nih.gov/pubmed/34230453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-021-00152-2
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