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Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation

Macrophages are key immune cells for the initiation and development of atherosclerotic lesions. However, the macrophage regulatory nodes that determine how lesions progress in response to dietary challenges are not fully understood. Liver X receptors (LXRs) are sterol-regulated transcription factors...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Gage, M. C., Bécares, N., Louie, R., Waddington, K. E., Zhang, Y., Tittanegro, T. H., Rodríguez-Lorenzo, S., Jathanna, A., Pourcet, B., Pello, O. M., De la Rosa, J. V., Castrillo, A., Pineda-Torra, I.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048484/
https://ncbi.nlm.nih.gov/pubmed/29950315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721245115
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