2290: Control of atherosclerosis regression by LXRα S198 phosphorylation

OBJECTIVES/SPECIFIC AIMS: Accumulation of cholesterol-laden macrophages in arterial walls leads to atherosclerosis. LXRs induce expression of genes that are atheroprotective in macrophages including CCR7, a chemokine receptor that promotes their emigration from the plaque. CCR7 expression has been s...

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Detalles Bibliográficos
Publicado en:J Clin Transl Sci
Main Authors: Shrestha, Elina, Voisin, Maud, Barrett, Tessa J., Nishi, Hitoo, Pineda-Torra, Inés, Fisher, Edward A., Garabedian, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: Cambridge University Press 2018
Assuntos:
Basic Science/Methodology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799160/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.34
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