LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression

We have previously shown that mouse atherosclerosis regression involves monocyte-derived (CD68(+)) cell emigration from plaques and is dependent on the chemokine receptor CCR7. Concurrent with regression, mRNA levels of the gene encoding LXRα are increased in plaque CD68(+) cells, suggestive of a fu...

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Hlavní autoři: Feig, Jonathan E., Pineda-Torra, Ines, Sanson, Marie, Bradley, Michelle N., Vengrenyuk, Yuliya, Bogunovic, Dusan, Gautier, Emmanuel L., Rubinstein, Daniel, Hong, Cynthia, Liu, Jianhua, Wu, Chaowei, van Rooijen, Nico, Bhardwaj, Nina, Garabedian, Michael J., Tontonoz, Peter, Fisher, Edward A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993578/
https://ncbi.nlm.nih.gov/pubmed/21041949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38911
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