LXRα regulates macrophage arginase 1 via PU.1 and IRF8

RATIONALE: Activation of Liver X Receptors (LXRs) inhibits the progression of atherosclerosis and promotes regression of existing lesions. In addition, LXRα levels are high in regressive plaques. Macrophage arginase 1 (Arg1) expression is inversely correlated with atherosclerosis progression and is...

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Autores principales: Pourcet, Benoit, Feig, Jonathan E, Vengrenyuk, Yuliya, Hobbs, Adrian, Kepka-Lenhart, Diane, Garabedian, Michael, Morris, Sidney M, Fisher, Edward A, Pineda-Torra, Inés
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180895/
https://ncbi.nlm.nih.gov/pubmed/21757649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.241810
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