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The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms
IL-18 is a member of the IL-1 family involved in innate immunity and inflammation. Deregulated levels of IL-18 are involved in the pathogenesis of multiple disorders including inflammatory and metabolic diseases, yet relatively little is known regarding its regulation. Liver X receptors or LXRs are...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858669/ https://ncbi.nlm.nih.gov/pubmed/27149934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25481 |
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