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A wild-type mouse-based model for the regression of inflammation in atherosclerosis

Atherosclerosis can be induced by the injection of a gain-of-function mutant of proprotein convertase subtilisin/kexin type 9 (PCSK9)–encoding adeno-associated viral vector (AAVmPCSK9), avoiding the need for knockout mice models, such as low-density lipoprotein receptor deficient mice. As regression...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Peled, Michael, Nishi, Hitoo, Weinstock, Ada, Barrett, Tessa J., Zhou, Felix, Quezada, Alexandra, Fisher, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349694/
https://ncbi.nlm.nih.gov/pubmed/28291840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173975
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