In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer

Genetic aberrations driving pro-oncogenic and pro-metastatic activity remain an elusive target in the quest of precision oncology. To identify such drivers, we use an animal model of KRAS-mutant lung adenocarcinoma to perform an in vivo functional screen of 217 genetic aberrations selected from lung...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Grzeskowiak, Caitlin L., Kundu, Samrat T., Mo, Xiulei, Ivanov, Andrei A., Zagorodna, Oksana, Lu, Hengyu, Chapple, Richard H., Tsang, Yiu Huen, Moreno, Daniela, Mosqueda, Maribel, Eterovic, Karina, Fradette, Jared J., Ahmad, Sumreen, Chen, Fengju, Chong, Zechen, Chen, Ken, Creighton, Chad J., Fu, Haian, Mills, Gordon B., Gibbons, Don L., Scott, Kenneth L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048166/
https://ncbi.nlm.nih.gov/pubmed/30013058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04572-3
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars