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Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase β
DNA polymerases accommodate various base pair conformations in the event of incorrect insertions. In particular, Watson-Crick-like dG:dTTP base pair has been observed at the insertion site of human DNA polymerase β (pol β). A potential factor contributing to the diverse conformations of base pair mi...
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| Veröffentlicht in: | Biochem J |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6048017/ https://ncbi.nlm.nih.gov/pubmed/29301983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170787 |
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