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Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase β

DNA polymerases accommodate various base pair conformations in the event of incorrect insertions. In particular, Watson-Crick-like dG:dTTP base pair has been observed at the insertion site of human DNA polymerase β (pol β). A potential factor contributing to the diverse conformations of base pair mi...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Koag, Myong-Chul, Lee, Seongmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048017/
https://ncbi.nlm.nih.gov/pubmed/29301983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170787
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