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Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication
A wide variety of endogenous and exogenous alkylating agents attack DNA to preferentially generate N7-alkylguanine (N7-alkylG) adducts. Studies on the effect of N7-alkylG lesions on biological processes have been difficult due in part to complications arising from the chemical lability of the positi...
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6113087/ https://ncbi.nlm.nih.gov/pubmed/29957995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00331 |
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