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N7 Methylation Alters Hydrogen Bonding Patterns of Guanine in Duplex DNA
N7-Alkyl-2′-deoxyguanosines are major adducts in DNA that are generated by various alkylating mutagens and drugs. However, the effect of the N7-alkylation on the hydrogen bonding patterns of the guanine remains poorly understood. We prepared N7-methyl-2′-deoxyguanosine (N7mdG)-containing DNA using a...
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| Yayımlandı: | J Am Chem Soc |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704973/ https://ncbi.nlm.nih.gov/pubmed/26517568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b10172 |
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