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Structural Basis for Promutagenicity of 8-Halogenated Guanine
8-Halogenated guanine (haloG), a major DNA adduct formed by reactive halogen species during inflammation, is a promutagenic lesion that promotes misincorporation of G opposite the lesion by various DNA polymerases. Currently, the structural basis for such misincorporation is unknown. To gain insight...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937695/ https://ncbi.nlm.nih.gov/pubmed/24425881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537803 |
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