A carregar...

Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine

Reactive oxygen species generate the genotoxic 8-oxoguanine (oxoG) and 8-oxoadenine (oxoA) as major oxidative lesions. The mutagenicity of oxoG is attributed to the lesion's ability to evade the geometric discrimination of DNA polymerases by adopting Hoogsteen base pairing with adenine in a Wat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Koag, Myong-Chul, Jung, Hunmin, Lee, Seongmin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229865/
https://ncbi.nlm.nih.gov/pubmed/32282906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa193
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!