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DNA interstrand cross-links induced by the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine

Oxidative damage to DNA generates 7,8-dihydro-8-oxoguanine (oxoG) and 7,8-dihydro-8-oxoadenine (oxoA) as two major lesions. Despite the comparable prevalence of these lesions, the biological effects of oxoA remain poorly characterized. Here we report the discovery of a class of DNA interstrand cross...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Rozelle, Aaron L., Cheun, Young, Vilas, Caroline K., Koag, Myong-Chul, Lee, Seongmin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997976/
https://ncbi.nlm.nih.gov/pubmed/33772030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22273-2
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