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Structural Basis for Promutagenicity of 8-Halogenated Guanine

8-Halogenated guanine (haloG), a major DNA adduct formed by reactive halogen species during inflammation, is a promutagenic lesion that promotes misincorporation of G opposite the lesion by various DNA polymerases. Currently, the structural basis for such misincorporation is unknown. To gain insight...

詳細記述

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書誌詳細
主要な著者: Koag, Myong-Chul, Min, Kyungjin, Lee, Seongmin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937695/
https://ncbi.nlm.nih.gov/pubmed/24425881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537803
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