Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer

BACKGROUND: Somatic mutations in the ERBB genes (epidermal growth factor receptor: EGFR, ERBB2, ERBB3, ERBB4) promote oncogenesis and lapatinib resistance in metastatic HER2+ (human epidermal growth factor-like receptor 2) breast cancer in vitro. Our study aimed to determine the frequency of mutatio...

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Detaylı Bibliyografya
Yayımlandı:Ther Adv Med Oncol
Asıl Yazarlar: Elster, Naomi, Toomey, Sinead, Fan, Yue, Cremona, Mattia, Morgan, Clare, Weiner Gorzel, Karolina, Bhreathnach, Una, Milewska, Malgorzata, Murphy, Madeline, Madden, Stephen, Naidoo, Jarushka, Fay, Joanna, Kay, Elaine, Carr, Aoife, Kennedy, Sean, Furney, Simon, Mezynski, Janusz, Breathhnach, Oscar, Morris, Patrick, Grogan, Liam, Hill, Arnold, Kennedy, Susan, Crown, John, Gallagher, William, Hennessy, Bryan, Eustace, Alex
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2018
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047239/
https://ncbi.nlm.nih.gov/pubmed/30023006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835918778297
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