Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies

BACKGROUND: The Cancer Genome Atlas analysis revealed that somatic EGFR, receptor tyrosine-protein kinase erbB-2 (ERBB2), Erb-B2 receptor tyrosine kinase 3 (ERBB3) and Erb-B2 receptor tyrosine kinase 4 (ERBB4) gene mutations (ERBB family mutations) occur alone or co-occur with somatic mutations in t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Breast Cancer Res
Prif Awduron: Toomey, Sinead, Eustace, Alexander J., Fay, Joanna, Sheehan, Katherine M., Carr, Aoife, Milewska, Malgorzata, Madden, Stephen F., Teiserskiene, Ausra, Kay, Elaine W., O’Donovan, Norma, Gallagher, William, Grogan, Liam, Breathnach, Oscar, Walshe, Janice, Kelly, Catherine, Moulton, Brian, Kennedy, M. John, Gullo, Guiseppe, Hill, Arnold D., Power, Colm, Duke, Deirdre, Hambly, Niamh, Crown, John, Hennessy, Bryan T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530949/
https://ncbi.nlm.nih.gov/pubmed/28750640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0883-9
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