Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies

BACKGROUND: The Cancer Genome Atlas analysis revealed that somatic EGFR, receptor tyrosine-protein kinase erbB-2 (ERBB2), Erb-B2 receptor tyrosine kinase 3 (ERBB3) and Erb-B2 receptor tyrosine kinase 4 (ERBB4) gene mutations (ERBB family mutations) occur alone or co-occur with somatic mutations in t...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Breast Cancer Res
Κύριοι συγγραφείς: Toomey, Sinead, Eustace, Alexander J., Fay, Joanna, Sheehan, Katherine M., Carr, Aoife, Milewska, Malgorzata, Madden, Stephen F., Teiserskiene, Ausra, Kay, Elaine W., O’Donovan, Norma, Gallagher, William, Grogan, Liam, Breathnach, Oscar, Walshe, Janice, Kelly, Catherine, Moulton, Brian, Kennedy, M. John, Gullo, Guiseppe, Hill, Arnold D., Power, Colm, Duke, Deirdre, Hambly, Niamh, Crown, John, Hennessy, Bryan T.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2017
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530949/
https://ncbi.nlm.nih.gov/pubmed/28750640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0883-9
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