Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies

BACKGROUND: The Cancer Genome Atlas analysis revealed that somatic EGFR, receptor tyrosine-protein kinase erbB-2 (ERBB2), Erb-B2 receptor tyrosine kinase 3 (ERBB3) and Erb-B2 receptor tyrosine kinase 4 (ERBB4) gene mutations (ERBB family mutations) occur alone or co-occur with somatic mutations in t...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Breast Cancer Res
المؤلفون الرئيسيون: Toomey, Sinead, Eustace, Alexander J., Fay, Joanna, Sheehan, Katherine M., Carr, Aoife, Milewska, Malgorzata, Madden, Stephen F., Teiserskiene, Ausra, Kay, Elaine W., O’Donovan, Norma, Gallagher, William, Grogan, Liam, Breathnach, Oscar, Walshe, Janice, Kelly, Catherine, Moulton, Brian, Kennedy, M. John, Gullo, Guiseppe, Hill, Arnold D., Power, Colm, Duke, Deirdre, Hambly, Niamh, Crown, John, Hennessy, Bryan T.
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2017
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530949/
https://ncbi.nlm.nih.gov/pubmed/28750640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0883-9
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