Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers

BACKGROUND: The application of genomic technologies to patient tumor samples identified groups of signaling pathways which acquire activating mutations. Some cancers are dependent on these mutations and the aberrant proteins resulting from these mutations can be targeted by novel drugs which can era...

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Bibliografiske detaljer
Udgivet i:Ther Adv Med Oncol
Main Authors: Milewska, Malgorzata, Cremona, Mattia, Morgan, Clare, O’Shea, John, Carr, Aoife, Vellanki, Sri HariKrishna, Hopkins, Ann M., Toomey, Sinead, Madden, Stephen F., Hennessy, Bryan T., Eustace, Alex J.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784557/
https://ncbi.nlm.nih.gov/pubmed/29383036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834017746040
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