Plasmin-Binding Tripeptide-Decorated Liposomes Loading Pyrazolo[3,4-d]pyrimidines for Targeting Hepatocellular Carcinoma

[Image: see text] Hepatocellular carcinoma (HCC) is one of the most fatal cancer types worldwide. HCC cells were proved to overexpress c-Src and Sgk1, a tyrosine and a serine-threonine kinase, respectively, whose role is crucial for the development and progression of the tumor. Pyrazolo[3,4-d]pyrimi...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Calandro, Pierpaolo, Iovenitti, Giulia, Zamperini, Claudio, Candita, Francesca, Dreassi, Elena, Chiariello, Mario, Angelucci, Adriano, Schenone, Silvia, Botta, Maurizio, Mancini, Arianna
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047171/
https://ncbi.nlm.nih.gov/pubmed/30034594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00062
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