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TREM2-Dependent Effects on Microglia in Alzheimer’s Disease

Alzheimer’s disease (AD) is a late-onset dementia characterized by the deposition of amyloid plaques and formation of neurofibrillary tangles (NFTs) which lead to neuronal loss and cognitive deficits. Abnormal protein aggregates in the AD brain are also associated with reactive microglia and astrocy...

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Pubblicato in:Front Aging Neurosci
Autori principali: Zhou, Yingyue, Ulland, Tyler K., Colonna, Marco
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046445/
https://ncbi.nlm.nih.gov/pubmed/30038567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00202
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