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TREM2-Dependent Effects on Microglia in Alzheimer’s Disease

Alzheimer’s disease (AD) is a late-onset dementia characterized by the deposition of amyloid plaques and formation of neurofibrillary tangles (NFTs) which lead to neuronal loss and cognitive deficits. Abnormal protein aggregates in the AD brain are also associated with reactive microglia and astrocy...

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Detalles Bibliográficos
Publicado en:Front Aging Neurosci
Main Authors: Zhou, Yingyue, Ulland, Tyler K., Colonna, Marco
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046445/
https://ncbi.nlm.nih.gov/pubmed/30038567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00202
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