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TREM2-Dependent Effects on Microglia in Alzheimer’s Disease

Alzheimer’s disease (AD) is a late-onset dementia characterized by the deposition of amyloid plaques and formation of neurofibrillary tangles (NFTs) which lead to neuronal loss and cognitive deficits. Abnormal protein aggregates in the AD brain are also associated with reactive microglia and astrocy...

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Опубликовано в: :Front Aging Neurosci
Главные авторы: Zhou, Yingyue, Ulland, Tyler K., Colonna, Marco
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046445/
https://ncbi.nlm.nih.gov/pubmed/30038567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00202
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