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TREM2-Dependent Effects on Microglia in Alzheimer’s Disease
Alzheimer’s disease (AD) is a late-onset dementia characterized by the deposition of amyloid plaques and formation of neurofibrillary tangles (NFTs) which lead to neuronal loss and cognitive deficits. Abnormal protein aggregates in the AD brain are also associated with reactive microglia and astrocy...
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| Publié dans: | Front Aging Neurosci |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6046445/ https://ncbi.nlm.nih.gov/pubmed/30038567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00202 |
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