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Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors

[Image: see text] Antibody–drug conjugates (ADCs) are a new class of anticancer therapeutics that combine the selectivity of targeted treatment, ensured by monoclonal antibodies, with the potency of the cytotoxic agent. Here, we applied an analogous approach, but instead of an antibody, we used fibr...

詳細記述

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書誌詳細
出版年:ACS Omega
主要な著者: Krzyscik, Mateusz Adam, Zakrzewska, Malgorzata, Sørensen, Vigdis, Sokolowska-Wedzina, Aleksandra, Lobocki, Michal, Swiderska, Karolina Weronika, Krowarsch, Daniel, Wiedlocha, Antoni, Otlewski, Jacek
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2017
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044718/
https://ncbi.nlm.nih.gov/pubmed/30023704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00116
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