An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease

Although the amyloid β-protein (Aβ) is believed to play an initiating role in Alzheimer’s disease (AD), the molecular characteristics of the key pathogenic Aβ forms are not well understood. As a result, it has proved difficult to identify optimal agents that target disease-relevant forms of Aβ. Here...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jin, Ming, O’Nuallain, Brian, Hong, Wei, Boyd, Justin, Lagomarsino, Valentina N., O’Malley, Tiernan T., Liu, Wen, Vanderburg, Charles R., Frosch, Matthew P., Young-Pearse, Tracy, Selkoe, Dennis J., Walsh, Dominic M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041266/
https://ncbi.nlm.nih.gov/pubmed/29992960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05068-w
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