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The aggregation paths and products of Aβ42 dimers are distinct from Aβ42 monomer
Extracts of Alzheimer's disease (AD) brain that contain what appear to be SDS-stable amyloid β-protein (Aβ) dimers potently block LTP and impair memory consolidation. Brain-derived dimers can be physically separated from Aβ monomer, consist primarily of Aβ42 and resist denaturation by powerful...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5461814/ https://ncbi.nlm.nih.gov/pubmed/27750419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00453 |
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