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Production and use of recombinant Aβ for aggregation studies

The amyloid β-protein (Aβ) is believed to play a central role in Alzheimer’s disease (AD) pathogenesis and there is great interest in understanding the process of Aβ aggregation, its underlying mechanism and the species generated during aggregation and their biological activity. Although Aβ has been...

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Détails bibliographiques
Publié dans:Methods Mol Biol
Auteurs principaux: O’Malley, Tiernan T., Linse, Sara, Walsh, Dominic M.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660832/
https://ncbi.nlm.nih.gov/pubmed/29744844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7811-3_19
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