Transcriptional Subtyping and CD8 Immunohistochemistry Identifies Patients With Stage II and III Colorectal Cancer With Poor Prognosis Who Benefit From Adjuvant Chemotherapy

PURPOSE: Transcriptomic profiling of colorectal cancer (CRC) has led to the identification of four consensus molecular subtypes (CMS1 to 4) that have prognostic value in stage II and III disease. More recently, the Colorectal Cancer Intrinsic Subtypes (CRIS) classification system has helped to defin...

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Detalhes bibliográficos
Publicado no:JCO Precis Oncol
Main Authors: Allen, Wendy L., Dunne, Philip D., McDade, Simon, Scanlon, Enya, Loughrey, Maurice, Coleman, Helen G., McCann, Christopher, McLaughlin, Kristy, Nemeth, Zsuzsanna, Syed, Najeeb Ashraf, Jithesh, Puthen Veettil, Arthur, Ken, Wilson, Richard, Coyle, Vicky M., McArt, Darragh, Murray, Graeme I., Samuel, Leslie, Nuciforo, Paolo, Jimenez, Jose, Argiles, Guillem, Dienstmann, Rodrigo, Tabernero, Josef, Picariello, Lucia, Messerini, Luca, Nobili, Stefania, Mini, Enrico, Sheahan, Kieran, Ryan, Elizabeth, Johnston, Patrick G., Van Schaeybroeck, Sandra, Lawler, Mark, Longley, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2018
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040635/
https://ncbi.nlm.nih.gov/pubmed/30088816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00241
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