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Identification of Candidate Small-Molecule Therapeutics to Cancer by Gene-Signature Perturbation in Connectivity Mapping

Connectivity mapping is a recently developed technique for discovering the underlying connections between different biological states based on gene-expression similarities. The sscMap method has been shown to provide enhanced sensitivity in mapping meaningful connections leading to testable biologic...

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Detalhes bibliográficos
Main Authors: McArt, Darragh G., Zhang, Shu-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031567/
https://ncbi.nlm.nih.gov/pubmed/21305029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016382
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