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A gene-signature progression approach to identifying candidate small-molecule cancer therapeutics with connectivity mapping

BACKGROUND: Gene expression connectivity mapping has gained much popularity recently with a number of successful applications in biomedical research testifying its utility and promise. Previously methodological research in connectivity mapping mainly focused on two of the key components in the frame...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Wen, Qing, Kim, Chang-Sik, Hamilton, Peter W., Zhang, Shu-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864913/
https://ncbi.nlm.nih.gov/pubmed/27170106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1066-x
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