AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early stage colon cancer

PURPOSE: Despite the use of 5-FU-based adjuvant treatments, a large proportion of high risk stage II/III colorectal cancer (CRC) patients will relapse. Thus, novel therapeutic strategies are needed for early stage CRC. Residual micrometastatic disease from the primary tumour is a major cause of pati...

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Main Authors: Dunne, Philip D., McArt, Darragh G., Blayney, Jaine K., Kalimutho, Murugan, Greer, Samanda, Wang, Tingting, Srivastava, Supriya, Ong, Chee Wee, Arthur, Ken, Loughrey, Maurice, Redmond, Keara, Longley, Daniel B., Salto-Tellez, Manuel, Johnston, Patrick G., Van Schaeybroeck, Sandra
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885388/
https://ncbi.nlm.nih.gov/pubmed/24170546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1354
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