EphA2 expression is a key driver of migration and invasion and a poor prognostic marker in colorectal cancer

PURPOSE: EphA2, a member of the Eph receptor tyrosine kinases family, is an important regulator of tumour initiation, neo-vascularization and metastasis in a wide range of epithelial and mesenchymal cancers, however its role in colorectal cancer (CRC) recurrence and progression is unclear. EXPERIMEN...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Dunne, Philip D., Dasgupta, Sonali, Blayney, Jaine K., McArt, Darragh G., Redmond, Keara L., Weir, Jessica-Anne, Bradley, Conor A., Sasazuki, Takehiko, Shirasawa, Senji, Wang, Tingting, Srivastava, Supriya, Ong, Chee Wee, Arthur, Ken, Salto-Tellez, Manuel, Wilson, Richard H., Johnston, Patrick G., Van Schaeybroeck, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694030/
https://ncbi.nlm.nih.gov/pubmed/26283684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0603
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