Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines

The in vitro generation of terminally differentiated hepatocytes is an unmet need. We investigated the contribution of oxygen concentration to differentiation in human liver cell lines HepaRG and C3A. HepaRG cells were cultured under hypoxia (5%O(2)), normoxia (21%O(2)) or hyperoxia (40%O(2)). Cultu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Cell Commun Signal
Main Authors: van Wenum, Martien, Adam, Aziza A. A., van der Mark, Vincent A., Chang, Jung-Chin, Wildenberg, Manon E., Hendriks, Erik J., Jongejan, Aldo, Moerland, Perry D., van Gulik, Thomas M., Oude Elferink, Ronald P., Chamuleau, Robert A. F. M., Hoekstra, Ruurdtje
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039343/
https://ncbi.nlm.nih.gov/pubmed/29399736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-018-0456-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados