A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines

Practice-changing culturing techniques of hepatocytes are highly required to increase their differentiation. Previously, we found that human liver cell lines HepaRG and C3A acquire higher functionality and increased mitochondrial biogenesis when cultured in the AMC-Bioartificial liver (BAL). Dynamic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Adam, Aziza A. A., van der Mark, Vincent A., Donkers, Joanne M., Wildenberg, Manon E., Oude Elferink, Ronald P. J., Chamuleau, Robert A. F. M., Hoekstra, Ruurdtje
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908182/
https://ncbi.nlm.nih.gov/pubmed/29672606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193664
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