Knockdown Indian Hedgehog (Ihh) does not delay Fibular Fracture Healing in genetic deleted Ihh mice and pharmaceutical inhibited Ihh Mice

The objective of this study was to determine if Ihh is required for fracture healing. Fibular fracture was created in adult Col2a1-CreER(T2); Ihh(fl)(/)(fl) mice. Ihh(fl)(/)(fl) mice received Tamoxifen (TM) to delete Ihh. WT mice received Cyclopamine to inhibit Hh pathway. Callus tissue properties a...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Li, Shengchun, Xiang, Chuan, Wei, Xiaochun, Li, Hongbin, Li, Kai, Sun, Xiaojuan, Wang, Shaowei, Zhang, Min, Deng, Jin, Wang, Xiaodu, Li, Pengcui, Li, Ruifang, Zhang, Yanxiang, Wei, Lei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037729/
https://ncbi.nlm.nih.gov/pubmed/29985470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28657-7
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