Knockdown Indian Hedgehog (Ihh) does not delay Fibular Fracture Healing in genetic deleted Ihh mice and pharmaceutical inhibited Ihh Mice

The objective of this study was to determine if Ihh is required for fracture healing. Fibular fracture was created in adult Col2a1-CreER(T2); Ihh(fl)(/)(fl) mice. Ihh(fl)(/)(fl) mice received Tamoxifen (TM) to delete Ihh. WT mice received Cyclopamine to inhibit Hh pathway. Callus tissue properties a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Li, Shengchun, Xiang, Chuan, Wei, Xiaochun, Li, Hongbin, Li, Kai, Sun, Xiaojuan, Wang, Shaowei, Zhang, Min, Deng, Jin, Wang, Xiaodu, Li, Pengcui, Li, Ruifang, Zhang, Yanxiang, Wei, Lei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037729/
https://ncbi.nlm.nih.gov/pubmed/29985470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28657-7
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi