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How cells ensure correct repair of DNA double-strand breaks
DNA double-strand breaks (DSBs) arise regularly in cells and when left unrepaired cause senescence or cell death. Homologous recombination (HR) and nonhomologous end-joining (NHEJ) are the two major DNA-repair pathways. Whereas HR allows faithful DSB repair and healthy cell growth, NHEJ has higher p...
Sparad:
| I publikationen: | J Biol Chem |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6036189/ https://ncbi.nlm.nih.gov/pubmed/29414795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.000371 |
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