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Introduction to the Thematic Minireview Series: DNA double-strand break repair and pathway choice

Environmental agents and reactive metabolites induce myriad chromosomal lesions that challenge the integrity of our genome. In particular, the DNA double-strand break (DSB) has the highest potential to cause the types of chromosome aberrations and rearrangements found in transformed and cancer cells...

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書目詳細資料
發表在:J Biol Chem
主要作者: Sung, Patrick
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036216/
https://ncbi.nlm.nih.gov/pubmed/29853635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.003212
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