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Introduction to the Thematic Minireview Series: DNA double-strand break repair and pathway choice

Environmental agents and reactive metabolites induce myriad chromosomal lesions that challenge the integrity of our genome. In particular, the DNA double-strand break (DSB) has the highest potential to cause the types of chromosome aberrations and rearrangements found in transformed and cancer cells...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autor principal: Sung, Patrick
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036216/
https://ncbi.nlm.nih.gov/pubmed/29853635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.003212
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