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BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites
The BLM gene product, BLM, is a RECQ helicase that is involved in DNA replication and repair of DNA double-strand breaks by the homologous recombination (HR) pathway. During HR, BLM has both pro- and anti-recombinogenic activities, either of which may contribute to maintenance of genomic integrity....
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5674892/ https://ncbi.nlm.nih.gov/pubmed/28912125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703144 |
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