Učitavanje...
Mutator Phenotype and DNA Double-Strand Break Repair in BLM Helicase-Deficient Human Cells
Bloom syndrome (BS), an autosomal recessive disorder of the BLM gene, predisposes sufferers to various cancers. To investigate the mutator phenotype and genetic consequences of DNA double-strand breaks (DSBs) in BS cells, we developed BLM helicase-deficient human cells by disrupting the BLM gene. Ce...
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| Izdano u: | Mol Cell Biol |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5108877/ https://ncbi.nlm.nih.gov/pubmed/27601585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00443-16 |
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