Wird geladen...

Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma

BACKGROUND: Standard treatment for advanced malignant pleural mesothelioma (MPM) is a cisplatin/pemetrexed (MTA) regimen; however, this is confronted by drug resistance. Proteotoxic stress in the endoplasmic reticulum (ER) is a hallmark of cancer and some rely on this stress signalling in response t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Br J Cancer
Hauptverfasser: Xu, Duo, Liang, Shun-Qing, Yang, Haitang, Lüthi, Ursina, Riether, Carsten, Berezowska, Sabina, Marti, Thomas M., Hall, Sean R. R., Bruggmann, Rémy, Kocher, Gregor J., Schmid, Ralph A., Peng, Ren-Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035279/
https://ncbi.nlm.nih.gov/pubmed/29921948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0145-3
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!